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Merz and Israeli company Vensica partner for needle-free treatment of overactive bladder

FRANKFURT, Germany, August 12, 2021– (BUSINESS WIRE) – Merz Therapeutics, a Merz Group company and chief within the area of neurotoxins, and Israeli startup Vensica Therapeutics Ltd., specializing within the area of urology, right now introduced their strategic settlement to license and collaboration for the administration of botulinum neurotoxin A (Xeomin®) into the bladder wall utilizing Vensica’s revolutionary ultrasound-assisted supply catheter. On this approach, Merz Therapeutics turns into the unique provider of toxins for any needleless utility indicated for urological situations, resembling overactive bladder, neurogenic bladder and interstitial cystitis amongst different urological indications.

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Vensica’s revolutionary ultrasound-assisted supply catheter for the needleless treatment of overactive bladder (Photograph: Enterprise Wire)

Stefan Brinkmann, CEO of Merz Therapeutics: “This long-term strategic partnership with Israeli start-up Vensica permits us to develop into the enticing overactive bladder market. It completely displays the potential and capabilities of our neurotoxin platform for the event of vital indications for non-movement problems, pursuing our promise to create higher outcomes for extra sufferers. ” We strongly imagine within the revolutionary and much less invasive treatment of bladder ailments utilizing Vensica’s ultrasound-assisted supply catheter and subsequently we’re wanting ahead to providing this new treatment choice to sufferers at the side of our partner Vensica. “

Vensica CEO Avner Geva commented: “We’re very enthusiastic about our strategic partnership with Merz. By licensing Merz’s Botulinum Toxin A, Xeomin®, we have now achieved an necessary milestone on our journey to alter the lives of urological sufferers. We hope that, along with Merz, we are able to provide needle-free and minimally invasive procedures to greater than 85 million sufferers worldwide, permitting them to profit from an outpatient expertise with out anesthesia and with minimal discomfort. The partnership with Merz, which incorporates not solely the unique license for Xeomin®, but additionally growth help, it permits us to speed up our scientific trials and regulatory course of. We’re delighted that Merz has realized the potential and want and has determined to spend money on applied sciences revolutionary medical options that may profit sufferers world wide. “

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“The collaboration with Vensica is a superb instance for our Merz company enterprise capital initiative,” says Jörg Bergler, Chief Working Officer of the Merz Group. “Right here we’re investing globally in firms pursuing groundbreaking and revolutionary science. As an skilled partner, we not solely grant Vensica entry to our toxin, however we additionally provide high quality information and experience for the event and preparation of the regulatory approval course of. of advisers. “

The long-term partnership contains Merz’s intention to take part and spend money on Vensica. Below the phrases of the settlement, Merz has already obtained, along with royalties, Vensica shares with an choice for new investments within the coming years and shall be represented with a place on the Board of Administrators. Vensica will deal with the preclinical and scientific growth of the needle-free machine and will put together and submit the advertising and marketing authorization utility. Upon approval of commercialization, Merz shall be accountable for the manufacture and provide of Xeomin® (incobotulinumtoxinA) and Vensica will handle the industrial actions worldwide, besides in Japan.

Vensica’s proprietary ultrasound-assisted drug supply system is an revolutionary minimally invasive resolution for urology. The system permits the administration of medication and not using a needle to the bladder wall in a easy and quick process. The platform encourages the efficiency of treatment relatively than in a surgical middle, in non-public clinics, because it eliminates the necessity for a extremely educated urologist, extra employees and anesthesia. The distinctive supply profile permits the uniform supply of the neurotoxin to a bigger space of ​​the bladder wall, which might enhance its efficacy, with an earlier onset and an extended impact. The machine is in scientific growth by Vensica Therapeutics, an Israel-based company.

Xeomin® is distributed by Merz Prescribed drugs GmbH in additional than 70 international locations for the treatment of sufferers with higher and decrease limb spasticity, cervical dystonia, blepharospasm or hypersalivation. Merz makes use of essentially the most superior expertise in its amenities in Dessau (Germany), complying with the best worldwide requirements for the manufacture of organic merchandise. The extremely purified neurotoxin, the one lively ingredient in Xeomin®, is manufactured by eradicating complexing proteins from botulinum toxin sort A, produced by Clostridium botulinum, utilizing a purification expertise developed by Merz Pharma GmbH & Co. KGaA. The absence of complexing proteins permits Xeomin® to scale back the manufacturing of neutralizing antibodies succesful of lowering efficacy.

About Merz Therapeutics

Merz Therapeutics, a Merz Prescribed drugs GmbH company, is devoted to bettering the lives of sufferers world wide. With its relentless analysis, growth and tradition of innovation, Merz Therapeutics strives to handle unmet affected person wants and obtain higher outcomes. Merz Therapeutics seeks to answer the particular wants of folks affected by motion problems, neurological situations, liver ailments and different well being issues that critically have an effect on the standard of life of sufferers. Merz Therapeutics is headquartered in Frankfurt, Germany, and is represented in additional than 90 international locations, with a North American affiliate in Raleigh, North Carolina. Merz Prescribed drugs GmbH is an element of the Merz Group, a non-public, family-owned company that has been devoted to growing improvements that meet the wants of sufferers and clients for over 110 years.

About Vensica Therapeutics Ltd.

Vensica is an Israel-based urology-focused therapeutic company. The company is growing a novel platform for the administration of medication indicated for numerous situations of the urinary bladder, primarily based by itself ultrasound-assisted drug supply system. The company was based in 2015 by Avner Geva, (Yale, B.Sc, Technion, M.Sc) and is led and endorsed by medical and therapeutic leaders, together with President MD, Ph.D, Nissim Darvish, Lew Pell, Laborie and The Trendlines Group.

About Merz

Merz is a diversified worldwide company, specializing in healthcare, primarily based in Frankfurt, Germany. Privately owned for greater than 112 years, the company operates within the areas of aesthetics, remedy and client care and is distinguished by its dedication to innovation, its long-term perspective and its deal with worthwhile development. Within the 2019/20 fiscal interval (June 30), Merz generated revenues of 981.5 million euros; It has a complete workforce of 3,212 staff in 28 international locations. For extra data, go to www.merz.com.

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Contacts

Press Contact
Merz Therapeutics, a enterprise of Merz Prescribed drugs GmbH
World Communications
+49 69 1503 2129
[email protected]

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